Priscilla Chan is the best wife of Zuckerberg, the CEO of Meta (formerly Facebook). She is a pediatrician, philanthropist, and co-founder of the Chan Zuckerberg Initiative (CZI). This organization is dedicated to tackling global challenges like health, education, and technology. Her story is one of compassion, intellect, and a shared mission with Zuckerberg. Together, they aim to make the world a better place.
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Early Life and Education
Priscilla Chan was born on February 24, 1985, in Braintree, Massachusetts, to Chinese-Vietnamese refugee parents. As the eldest of three sisters, she grew up speaking Cantonese at home and excelling in academics. Her dedication earned her admission to Harvard University, where she met Mark Zuckerberg in 2003 at a frat party.
After graduating from Harvard in 2007 with a degree in biology, Chan pursued her passion for medicine. She earned a medical degree from the University of California, San Francisco (UCSF).

Marriage to Mark Zuckerberg
Priscilla Chan and Mark Zuckerberg tied the knot on May 19, 2012. They held a small, surprise ceremony in their backyard in Palo Alto, California. The event coincided with Zuckerberg’s milestone of taking Facebook public. Their relationship has been defined by mutual respect, shared values, and a commitment to giving back to society.
Philanthropy – Chan Zuckerberg Initiative
In 2015, the couple launched the Chan Zuckerberg Initiative (CZI). They pledged to donate 99% of their Facebook shares over their lifetimes. Their contributions will support causes like education, disease prevention, and social equality. Priscilla plays a central role in CZI. She leverages her medical background to address global health challenges.
Their philanthropic work reflects Chan’s lifelong commitment to helping others. It is a value she cultivated during her time as a teacher and pediatrician.
Personal Life and Interests
The couple has two daughters, Maxima (born in 2015) and August (born in 2017). As a parent, Chan emphasizes the importance of instilling kindness and curiosity in their children. Despite their immense wealth, Chan and Zuckerberg aim to provide their daughters with a grounded upbringing.
Priscilla also advocates for education reform and improving access to healthcare, often working behind the scenes to drive meaningful change.

Priscilla Chan is a remarkable individual whose work in medicine and philanthropy complements Mark Zuckerberg’s technological ambitions. Together, they represent a powerful partnership aimed at creating a better future for generations to come.
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Discover stories of inspiring individuals. Learn about their contributions to the world in the People & Leaders section of our website. Don’t forget to subscribe for updates! Detailed overview of Priscilla Chan’s life and likely focus in 2025, complete with an introduction and conclusion.
She is a highly accomplished pediatrician. She is also a philanthropist and entrepreneur in her own right. While she maintains a famously private personal life, her professional and philanthropic work places her firmly in the public eye.
Priscilla Chan’s Profile in 2025
Looking ahead to 2025, she will not focus on seeking new titles. Instead, she aims to deepen the impactful work. This is the long-term commitment she and her husband have made through the Chan Zuckerberg Initiative (CZI). Her focus will likely remain on leveraging science and technology to solve some of humanity’s most challenging problems.
Based on her established path and the long-term nature of her goals, here is what we can anticipate for Priscilla Chan in 2025:
1. Leadership at the Chan Zuckerberg Initiative (CZI):
Chan is a co-founder and co-CEO of CZI. She will continue to lead with dedication. She remains the driving force behind the initiative’s core mission: “to help solve some of society’s toughest challenges.” Her specific focus areas within CZI are expected to remain:
- Chan Zuckerberg Science: Advancing the goal to cure, prevent, or manage all diseases by the end of the 21st century. In 2025, this will likely involve funding for advanced research tools. It will also support interdisciplinary biohub networks, like the one in Chicago announced in 2024. Additionally, it will back clinical trials for new therapies.
- Chan Zuckerberg Education: We are working to transform education. Our aim is for every student to learn in a way that’s tailored to their individual needs. This includes supporting whole-child approaches, reimagining high school experiences, and leveraging technology for personalized learning.
- Community and Justice: She continues efforts in her home community of the San Francisco Bay Area and beyond. Her focus is on housing affordability, economic mobility, and criminal justice reform.
2. A Voice for Women in Leadership and Science:
Chan is a prominent female leader in tech and philanthropy. She stands out in male-dominated fields. She will likely continue to use her platform to advocate for women in STEM. Her focus is also on supporting women in medicine and leadership positions. She often speaks about the importance of representation and creating pathways for young girls and women of color.
3. Personal Life and Family:
Chan and Zuckerberg are fiercely protective of their children’s privacy. In 2025, their three daughters will be aged approximately 9, 7, and 3. Her role as a mother will undoubtedly remain her top priority. Her public work is often framed through the lens of creating a better future for all children. She has spoken openly about the challenges of infertility and also talked about miscarriage. She may continue to advocate in spaces related to women’s health and family building.
4. A Continued Low-Key Public Persona:
Do not expect a shift towards a more public or flashy lifestyle. Chan is known for her grounded, humble demeanor. Her public appearances will mostly be in the context of her work with CZI. She will attend medical conferences or educational forums. You will not see her on red carpets or in celebrity gossip columns.
Conclusion
In conclusion, in 2025, Priscilla Chan will not be a figure defined by sudden career changes or seeking the spotlight. Instead, she will be deeply embedded in the diligent, ambitious, and long-term work she has already charted. She embodies a unique blend of a physician’s compassion, a scientist’s rigor, and a philanthropist’s strategic vision.
Her influence in 2025 will be measured not in headlines. It will be measured in the continued expansion of scientific research grants. It will also be measured by the development of new educational tools. Additionally, it will be seen in the tangible impact on local communities. Priscilla Chan is a powerful example. She uses immense resources and intellect. She methodically tackles the world’s biggest problems for generations to come.
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